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Article

[Mutations of genes associated with thromboses in ischemic stroke in patients with primary antiphospholipid syndrome].

Terapevticheskii arkhiv - 1 Jan 2005

Kalashnikova L A, Dobrynina L A, Patrusheva N L, Kovalenko T F, Patrushev L I, Aleksandrova E N, Berkovskiĭ A L, Sergeeva E V, Nasonov E L

Abstract excerpt

AIM: To study factor V Leiden, prothrombin (G1691A), 5, 10-methylenetetrahydrofolate reductase (MTHFR, C677T) mutations in patients with primary antiphospholipid syndrome (PAPS) and cerebrovascular disease (CVD). MATERIAL AND METHODS: We studied 44 patients (38 female, 6 male, mean age 41.6 +/- 11.6 years) with PAPS and CVD. Detection of mutations was carried out using polymerase chain reaction. RESULTS:...

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Identifiers

PMID: 16320685

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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