Article
Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells.
Toxicology and applied pharmacology - 1 Jun 2006
Du Liping, Neis Mark M, Ladd Patricia A, Lanza Diane L, Yost Garold S, Keeney Diane S
Abstract excerpt
Epoxyeicosatrienoic acids produced by mouse CYP2B19 have been implicated in mechanisms regulating epidermal cornification (Ladd, P.A., Du, L., Capdevila, J.H., Mernaugh, R., Keeney, D.S., 2003. Epoxyeicosatrienoic acids activate transglutaminases in situ and induce cornification of epidermal keratinocytes. J. Biol. Chem. 278, 35184-35192). In this study, we aimed to identify CYPs that are up-regulated during...
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