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Article

Genetic heterogeneity in association of the SUMO4 M55V variant with susceptibility to type 1 diabetes.

Diabetes - 1 Dec 2005

Noso Shinsuke, Ikegami Hiroshi, Fujisawa Tomomi, Kawabata Yumiko, Asano Katsuaki, Hiromine Yoshihisa, Tsurumaru Masako, Sugihara Shigetaka, Lee Inkyu, Kawasaki Eiji, Awata Takuya, Ogihara Toshio

Abstract excerpt

Association studies are a potentially powerful approach to identifying susceptibility variants for common multifactorial diseases such as type 1 diabetes, but the results are not always consistently reproducible. The IDDM5 locus has recently been narrowed to an approximately 200-kb interval on ch...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16306380
DOI: 10.2337/diabetes.54.12.3582

Genes

SUMO4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16306380-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Genetic heterogeneity in association of the SUMO4 M55V variant with susceptibility to type 1 diabetes.PMID 16306380Read ↗

Association of SUMO4, as a candidate gene for IDDM5, with susceptibility to type 1 diabetes in Asian populations.Semantic proximity Read ↗

Association of small ubiquitin-like modifier 4 (SUMO4) variant, located in IDDM5 locus, with type 2 diabetes in the Japanese population.Semantic proximity Read ↗

Association of SUMO4 M55V polymorphism with type 1 diabetes in Chinese children.Semantic proximity Read ↗

Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene.Semantic proximity Read ↗

Analyses of multiple single-nucleotide polymorphisms in the SUMO4/IDDM5 region in affected sib-pair families with type I diabetes.Semantic proximity Read ↗

Polymorphism M55V in gene encoding small ubiquitin-like modifier 4 (SUMO4) protein associates with susceptibility to type 1 (and type 2) diabetes.Semantic proximity Read ↗

SUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients.Semantic proximity Read ↗

Association of SUMO4 Met55Val variation with increased insulin resistance in newly diagnosed type 2 diabetes in a Chinese population.Semantic proximity Read ↗

SUMO4 and its role in type 1 diabetes pathogenesis.Semantic proximity Read ↗

Association between the SUMO4 M55V Polymorphism and Susceptibility to Type 2 Diabetes Mellitus: A Meta-analysis.Semantic proximity Read ↗

Association between the SUMO4 M55V (A163G) polymorphism and susceptibility to type 1 diabetes: a meta-analysis.Semantic proximity Read ↗

Sumoylation Modulates the Susceptibility to Type 1 Diabetes.Semantic proximity Read ↗

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