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Article

Genetic basis of tetrodotoxin resistance in pufferfishes.

Current biology : CB - 22 Nov 2005

Venkatesh Byrappa, Lu Song Qing, Dandona Nidhi, See Shean Long, Brenner Sydney, Soong Tuck Wah

Abstract excerpt

Tetrodotoxin (TTX) is a highly potent neurotoxin that selectively binds to the outer vestibule of voltage-gated sodium channels. Pufferfishes accumulate extremely high concentrations of TTX without any adverse effect. A nonaromatic amino acid (Asn) residue present in domain I of the pufferfish, Takifugu pardalis, Na v1.4 channel has been implicated in the TTX resistance of pufferfishes . However, the effect of...

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Identifiers

PMID: 16303569
DOI: 10.1016/j.cub.2005.10.068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Genetic basis of tetrodotoxin resistance in pufferfishes.PMID 16303569Read ↗

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