Article
"Clonal" population structure of the malaria agent Plasmodium falciparum in high-infection regions.
Proceedings of the National Academy of Sciences of the United States of America - 29 Nov 2005
Razakandrainibe F G, Durand P, Koella J C, De Meeüs T, Rousset F, Ayala F J, Renaud F
Abstract excerpt
The population genetic structure of Plasmodium falciparum, the agent of malignant malaria, has been shown to be predominantly "clonal" (i.e., highly inbred) in regions of low infectivity; in high-infectivity regions, it is often thought to be panmictic, or nearly so, although there is little supporting evidence for this. The matter can be settled by investigating the parasite's genetic makeup in the midgut...
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