Article
Genotype/phenotype correlations in X-linked agammaglobulinemia.
Clinical immunology (Orlando, Fla.) - 1 Jan 2000
Broides Arnon, Yang Wenjian, Conley Mary Ellen
Abstract excerpt
No clear genotype/phenotype correlations have been established in patients with X-linked agammaglobulinemia (XLA). To determine if the specific mutation in Btk might be one of the factors that influences the severity of disease or if polymorphic variants in Tec, a cytoplasmic tyrosine kinase that might substitute for Btk, could contribute to the clinical phenotype, we examined the age at diagnosis, the percentage...
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