Article
The predicted impact of coding single nucleotide polymorphisms database.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2005
Rudd Matthew F, Williams Richard D, Webb Emily L, Schmidt Steffen, Sellick Gabrielle S, Houlston Richard S
Abstract excerpt
Nonsynonymous single nucleotide polymorphisms (nsSNP) have the potential to affect the structure or function of expressed proteins and are, therefore, likely to represent modifiers of inherited susceptibility. We have classified and catalogued the predicted functionality of nsSNPs in genes relevant to the biology of cancer to facilitate sequence-based association studies. Candidate genes were identified using...
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