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Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts

3 Oct 2005

Abstract excerpt

INTRODUCTION: Adjuvant breast cancer therapy significantly improves survival, but overtreatment and undertreatment are major problems. Breast cancer expression profiling has so far mainly been used to identify women with a poor prognosis as candidates for adjuvant therapy but without demonstrated value for therapy prediction. METHODS: We obtained the gene expression profiles of 159 population-derived breast...

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PMID: 16280042
DOI: 10.1186/bcr1325

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