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Article

Survival of the fittest: in vivo selection and stem cell gene therapy.

Blood - 1 Mar 2006

Neff Tobias, Beard Brian C, Kiem Hans-Peter

Abstract excerpt

Stem cell gene therapy has long been limited by low gene transfer efficiency to hematopoietic stem cells. Recent years have witnessed clinical success in select diseases such as X-linked severe combined immunodeficiency (SCID) and ADA deficiency. Arguably, the single most important factor responsible for the increased efficacy of these recent protocols is the fact that the genetic correction provided a selective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to O(6)-Methylguanine-DNA Methyltransferase

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Source

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Identifiers

PMID: 16269617
DOI: 10.1182/blood-2005-06-2335
PMCID: PMC1895696

Genes

ADA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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