Article
[The AGT genotype affects the antihypertensive effects of benazepril].
Zhonghua xin xue guan bing za zhi - 1 Sept 2005
Yu Hui-min, Lin Shu-guang, Zhang Yu-qing, Ma We-jun, Liu Guo-zhang
Abstract excerpt
OBJECTIVE: To investigate the association between M235T variant of angiotensinogen (AGT) gene and the blood pressure response to benazepril in a hypertensive cohort. METHODS: Benazepril (10-20 mg/day) was administered for 6 weeks to 251 essential hypertensives. Polymerase chain reaction (PCR) combined with restriction enzyme digestion was used to detect the polymorphism and the patients were classified as MM, MT...
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