The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia.

doi:10.1371/journal.pgen.0010050

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Article

The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia.

PLoS genetics - 1 Oct 2005

Hannula-Jouppi Katariina, Kaminen-Ahola Nina, Taipale Mikko, Eklund Ranja, Nopola-Hemmi Jaana, Kääriäinen Helena, Kere Juha

Abstract excerpt

Dyslexia, or specific reading disability, is the most common learning disorder with a complex, partially genetic basis, but its biochemical mechanisms remain poorly understood. A locus on Chromosome 3, DYX5, has been linked to dyslexia in one large family and speech-sound disorder in a subset of small families. We found that the axon guidance receptor gene ROBO1, orthologous to the Drosophila roundabout gene, is...

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Identifiers

PMID: 16254601
DOI: 10.1371/journal.pgen.0010050
PMCID: PMC1270007

Genes

ROBO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.