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Article

Study of the active site residues of a glycoside hydrolase family 8 xylanase.

Journal of molecular biology - 25 Nov 2005

Collins T, De Vos D, Hoyoux A, Savvides S N, Gerday C, Van Beeumen J, Feller G

Abstract excerpt

Site-directed mutagenesis and a comparative characterisation of the kinetic parameters, pH dependency of activity and thermal stability of mutant and wild-type enzymes have been used in association with crystallographic analysis to delineate the functions of several active site residues in a novel glycoside hydrolase family 8 xylanase. Each of the residues investigated plays an essential role in this enzyme: E78...

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Source

Identifiers

PMID: 16246370
DOI: 10.1016/j.jmb.2005.09.064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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