Article
A new germline mutation in BRCA1 gene in a sicilian family with ovarian cancer.
Breast cancer research and treatment - 1 Mar 2006
Calò Valentina, Agnese Valentina, Gargano Grazia, Corsale Simona, Gregorio Valter, Cascio Sandra, Cammareri Patrizia, Bruno Loredana, Augello Claudia, Gullo Arianna, Sisto Pasqua Sandra, Badalamenti Giuseppe, Valerio Maria Rosaria, Napoli Liborio, Gebbia Nicola, Bazan Viviana, Russo Antonio
Abstract excerpt
A group of 103 sicilian patients with hereditary and familiar breast and/or ovarian cancer were screened for Breast Cancer 1 gene (BRCA1) mutations by direct sequencing PCR products spanning the coding region and partial intronic regions of the BRCA1 gene. In this study, we report a new germline mutation in BRCA1 gene, not previously reported in the BIC database, in a woman with ovarian cancer at 46 years old....
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