Article
[Heme oxygenase 1 expression in foundry workers].
Giornale italiano di medicina del lavoro ed ergonomia - 1 Jan 2000
Mozzoni P, De Palma G, Scotti E, Andreoli R, Folesani G, Maninil P, Apostoli P, Mutti A
Abstract excerpt
Heme oxygenase 1 (HO-1) catalyses the oxidation of heme to biliverdin, and its expression is induced by oxidative stress. This study was aimed at assessing the role of metabolic polymorphisms (CYP1A1, CYP1B1, GSTM1, GSTP1, EPHX) in the modulation of HO-1 gene expression in 37 foundry workers. Blood and urine samples were obtained at the beginning (BS) and at the end (ES) of work shift, in February (T1) and June...
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