Article
Genotyping--from genomic DNA to genotype in a single tube.
Angewandte Chemie (International ed. in English) - 9 Dec 2005
Strerath Michael, Marx Andreas
Abstract excerpt
Nucleotide variations in the human genome, such as single-nucleotide polymorphisms, have been researched more intensively since it became apparent that these deviations are linked to various diseases and also several side effects of drugs. The investigation of genomic DNA in the laboratory requires routine methods that are time-, labour-, and cost-effective. These criteria are fulfilled by so-called closed-tube...
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