Article
Lipoprotein-associated phospholipase A2 activity is a marker of small, dense LDL particles in human plasma.
Clinical chemistry - 1 Dec 2005
Gazi Irene, Lourida Evangelia S, Filippatos Theodosios, Tsimihodimos Vasilis, Elisaf Moses, Tselepis Alexandros D
Abstract excerpt
BACKGROUND: Recent clinical studies showed that lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a predictor for incident atherosclerotic disease. We have previously shown that among the LDL subfractions, Lp-PLA(2) activity is preferentially associated with the atherogenic small, dense (sdLDL) particles in vitro. We investigated whether Lp-PLA(2) could be a marker of sdLDL in human plasma. METHODS: One...
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