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Article

Comparison of In Vitro and In Vivo Screening Models for Androgenic and Estrogenic Activities

12 Oct 2005

Abstract excerpt

Identification of nuclear receptor-mediated endocrine activities is important in a variety of fields, ranging from pharmacological and clinical screening, to food and feed safety, toxicological monitoring, and risk assessment. Traditionally animal studies such as the Hershberger and Allen-Doisy tests are used for the assessment of androgenic and estrogenic potencies, respectively. To allow fast analysis of the...

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Share to Effects and risks of endocrine disrupting chemicals
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16221957
DOI: 10.1093/toxsci/kfj009

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