Article
Differential inhibition of fat intake in two strains of rat by the peptide enterostatin.
The American journal of physiology - 1 Jun 1992
Okada S, York D A, Bray G A, Mei J, Erlanson-Albertsson C
Abstract excerpt
The effect of enterostatin, the amino-terminal pentapeptide of pancreatic procolipase, on food intake was investigated in two strains of rat, the dietary fat-sensitive Osborne-Mendel (OM) rat and the dietary fat-resistant S5B/Pl rat. After an overnight fast, enterostatin inhibited intake of high-fat (HF) but not low-fat (LF) diets in OM rats, but had no effect in S5B/Pl rats. When fed a macronutrient three-choice...
Topics
- Animals
- Colipases
- Dietary Fats
- Eating
- Enzyme Precursors
- Fasting
- Food Preferences
- Genetic Predisposition to Disease
- Male
- Obesity
- Pancreas
- Protein Precursors