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Article

Mutational landscape of B-cell post-transplant lymphoproliferative disorders.

British journal of haematology - 1 Jul 2017

Menter Thomas, Juskevicius Darius, Alikian Mary, Steiger Juerg, Dirnhofer Stephan, Tzankov Alexandar, Naresh Kikkeri N

Abstract excerpt

It is currently unclear whether post-transplant diffuse large B-cell lymphomas (PT-DLBCL) display a similar genomic landscape as DLBCL in immunocompetent patients (IC-DLBCL). We investigated 50 post-transplant lymphoproliferative disorders (PTLDs) including 37 PT-DLBCL samples for somatic mutations frequently observed in IC-DLBCL. Targeted Next Generation Sequencing (NGS) using the Ion Torrent platform and a...

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PMID: 28419429
DOI: 10.1111/bjh.14633

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