Article
Tissue-specific regulation of cell-cycle responses to DNA damage in Arabidopsis seedlings.
DNA repair - 5 Jan 2006
Hefner Eli, Huefner Neil, Britt Anne B
Abstract excerpt
DNA damage-induced cell-cycle "checkpoint" responses reduce the mutagenic effects of this damage. However, the maintenance of genomic stability comes at a price: the slowing of growth and a delay in the development of critical tissues. In mammals, every mutated cell has the potential to become cancerous and therefore lethal. In plants, the risk of lethal cancers is essentially nil and the costs of delays in...
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