Article
Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach
27 Sept 2005
Abstract excerpt
BACKGROUND AND AIM: A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with culture independent molecular approaches. METHODS: We used, for the first time, a comprehensive metagenomic approach to investigate the full range of intestinal microbial diversity. We...
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