Article
Simple repeat sequences on the human Y chromosome are equally polymorphic as their autosomal counterparts.
Human genetics - 1 Jun 1992
Roewer L, Arnemann J, Spurr N K, Grzeschik K H, Epplen J T
Abstract excerpt
The human genome contains a large number of interspersed simple repeat sequences that are variable in length and can therefore serve as highly informative, polymorphic markers. Typing procedures include conventional multilocus and single locus probing, and polymerase chain reaction aided analysis. We have identified simple sequences in a cosmid clone stemming from the human Y chromosome and consisting of (gata)n...
Topics
- Base Sequence
- Chromosomes, Human, Pair 12
- Humans
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Repetitive Sequences, Nucleic Acid
- Y Chromosome
