Article
Role of HtrA in surface protein expression and biofilm formation by Streptococcus mutans.
Infection and immunity - 1 Oct 2005
Biswas Saswati, Biswas Indranil
Abstract excerpt
The HtrA surface protease in gram-positive bacteria is involved in the processing and maturation of extracellular proteins and degradation of abnormal or misfolded proteins. Inactivation of htrA has been shown to affect the tolerance to thermal and environmental stress and to reduce virulence. We found that inactivation of Streptococcus mutans htrA by gene-replacement also resulted in a reduced ability to...
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