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Article

Herpes simplex virus and varicella-zoster virus: why do these human alphaherpesviruses behave so differently from one another?

1 Jan 2005

Abstract excerpt

Members of the Herpesviridae family of viruses are classified into the alpha, beta and gamma subfamilies. The alpha subfamily is estimated to have diverged from the beta and gamma subfamilies 200-220 million years ago. The ancestors of the herpes simplex virus (HSV) and the varicella-zoster virus (VZV), two ubiquitous and clinically important human pathogens, appeared 70-80 million years ago. As these viruses...

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PMID: 16173110
DOI: 10.1002/rmv.478

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