Article
Regulation of macrophage phenotype by long-term exposure to IL-10.
Immunobiology - 1 Jan 2005
Park-Min Kyung-Hyun, Antoniv Taras T, Ivashkiv Lionel B
Abstract excerpt
Macrophages are chronically exposed to IL-10 in a variety of physiological and pathological settings. Macrophage responses to short-term stimulation with IL-10 have been extensively studied, but the effects of chronic exposure to IL-10 on macrophage function are not known. Herein we used transcriptional profiling and functional studies to characterize the phenotype of macrophages after long-term culture with...
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