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Stem-Loop IV in the 5′ Untranslated Region Is a <i>cis</i> -Acting Element in Bovine Coronavirus Defective Interfering RNA Replication

14 Sept 2005

Abstract excerpt

The 210-nucleotide (nt) 5' untranslated region (UTR) in the positive-strand bovine coronavirus (BCoV) genome is predicted to contain four higher-order structures identified as stem-loops I to IV, which may function as cis-acting elements in genomic RNA replication. Here, we describe evidence that stem-loop IV, a bulged stem-loop mapping at nt 186 through 215, (i) is phylogenetically conserved among group 2...

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Identifiers

PMID: 16160171
DOI: 10.1128/jvi.79.19.12434-12446.2005

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