Article
Promoter hypermethylation of the potential tumor suppressor <i>DAL‐1/4.1B</i> gene in renal clear cell carcinoma
8 Sept 2005
Abstract excerpt
Renal clear cell carcinoma (RCCC) is a malignant tumor with poor prognosis caused by the high incidence of metastasis to distal organs. Although metastatic RCCC cells frequently show aberrant cytoskeletal organization, the underlying mechanism has not been elucidated. DAL-1/4.1B is an actin-binding protein implicated in the cytoskeleton-associated processes, while its inactivation is frequently observed in lung...
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