Article
Primary gastrointestinal stromal tumor of the liver with lung metastases successfully treated with STI-571 (imatinib mesylate).
Frontiers in bioscience : a journal and virtual library - 1 Jan 2006
De Chiara Annarosaria, De Rosa Vincenzo, Lastoria Secondo, Franco Renato, Botti Gerardo, Iaffaioli Vincenzo Rosario, Apice Gaetano
Abstract excerpt
We report a case of a primary malignant GIST of the liver metastatic to the lung in a 37 years-old man. The liver tumor showed histological feature of a GIST and expressed vimentin, and diffusely exhibited CD117. One year after the resection of the liver mass, the patient developed multiple small lung metastases which completely disappeared with STI-571 (imatinib mesylate--Gleevec) therapy. C.T. or PET did not...
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