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Article

Natural and synthetic alleles provide complementary insights into the nature of selection acting on the Men polymorphism of Drosophila melanogaster.

Genetics - 1 Dec 2005

Merritt Thomas J S, Duvernell David, Eanes Walter F

Abstract excerpt

Two malic enzyme alleles, Men(113A) and Men(113G), occur at approximately equal frequency in North American populations of Drosophila melanogaster, while only Men(113A) occurs in African populations. We investigated the population genetics, biochemical characteristics, and selective potential of these alleles. Comparable levels of nucleotide polymorphism in both alleles suggest that the Men(113G) allele is not...

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Identifiers

PMID: 16143603
DOI: 10.1534/genetics.105.048249
PMCID: PMC1456097

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