Article
Major histocompatibility complex and alveolar epithelial apoptosis in idiopathic pulmonary fibrosis.
Human genetics - 1 Nov 2005
Falfán-Valencia Ramcés, Camarena Angel, Juárez Armida, Becerril Carina, Montaño Martha, Cisneros José, Mendoza Felipe, Granados Julio, Pardo Annie, Selman Moisés
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by fibroblast expansion, and tissue remodeling. It is considered a multifactorial disease but the possible involved genes are largely unknown. Interestingly, studies regarding the possible role of major histocompatibility complex (MHC) are scanty and show contradictory results. In this study, we evaluated the polymorphisms of the MHC, locus...
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