Article
Lack of association of PAX4 gene with type 1 diabetes in the Finnish and Hungarian populations.
Diabetes - 1 Sept 2005
Hermann Robert, Mantere Jussi, Lipponen Kati, Veijola Riitta, Soltesz Gyula, Otonkoski Timo, Simell Olli, Knip Mikael, Ilonen Jorma
Abstract excerpt
We aimed to assess the possible contribution of the PAX4 transcription factor gene to the genetic background of type 1 diabetes. We analyzed four coding polymorphisms of the PAX4 gene in 498 cases with type 1 diabetes and 825 control subjects from Finland and Hungary. All patients were diagnosed under the age of 15 years according to the World Health Organization criteria. All four PAX4 variants (three in exon 9...
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