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Article

Mechanism for the homocysteine-enhanced antifibrinolytic potential of lipoprotein(a) in human plasma.

Thrombosis and haemostasis - 1 Jul 2005

Nardulli Marina, Durlach Vincent, Pepe Gabriella, Anglés-Cano Eduardo

Abstract excerpt

Lipoprotein(a) and total plasma homocysteine levels are now established as independent atherothrombogenic risk factors. A distinctive pathophysiological feature of lipoprotein(a) is its antifibrinolytic activity, an effect dependent on plasma concentration and high affinity for fibrin of its small size apo(a) component. A stimulating effect of homocysteine on purified lipoprotein(a) has been proposed. However,...

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Identifiers

PMID: 16113787
DOI: 10.1160/TH04-12-0808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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