Article
Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases.
Proceedings of the National Academy of Sciences of the United States of America - 30 Aug 2005
Stevenson-Paulik Jill, Bastidas Robert J, Chiou Shean-Tai, Frye Roy A, York John D
Abstract excerpt
Phytate (inositol hexakisphosphate, IP6) is a regulator of intracellular signaling, a highly abundant animal antinutrient, and a phosphate store in plant seeds. Here, we report a requirement for inositol polyphosphate kinases, AtIPK1 and AtIPK2beta, for the later steps of phytate synthesis in Arabidopsis thaliana. Coincident disruption of these kinases nearly ablates seed phytate without accumulation of phytate...
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