Article
Design issues in cross-sectional biomarkers studies: urinary biomarkers of PAH exposure and oxidative stress.
Mutation research - 30 Dec 2005
Kang Daehee, Lee Kyoung-Ho, Lee Kyoung-Mu, Kwon Ho-Jang, Hong Yun-Chul, Cho Soo-Hun, Strickland Paul T
Abstract excerpt
Cross-sectional biomarker studies can provide a snapshot of the frequency and characteristics of exposure/disease in a population at a particular point in time and, as a result, valuable insights for delineating the multi-step association between exposure and disease occurrence. Three major issues should be considered when designing biomarker studies: selection of appropriate biomarkers, the assay (laboratory...
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