Article
The V1a vasopressin receptor is necessary and sufficient for normal social recognition: a gene replacement study.
Neuron - 18 Aug 2005
Bielsky Isadora F, Hu Shuang-Bao, Ren Xianghui, Terwilliger Ernest F, Young Larry J
Abstract excerpt
Vasopressin modulates many social and nonsocial behaviors, including emotionality. We have previously reported that male mice with a null mutation in the V1a receptor (V1aR) exhibit a profound impairment in social recognition and changes in anxiety-like behavior. Using site-specific injections of a V1aR-specific antagonist, we demonstrate that the lateral septum, but not the medial amygdala, is critical for...
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