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Article

The evolution and maintenance of polymorphism in the major histocompatibility complex.

Veterinary immunology and immunopathology - 18 Oct 2005

Stear M J, Innocent G T, Buitkamp J

Abstract excerpt

Lambs with the G2 allele at the ovine major histocompatibility complex (mhc) class II locus DRB1 has previously been shown to have lower faecal nematode egg counts than lambs with the I allele at this locus. This association has been confirmed in separate cohorts from the same farm. Other alleles within the mhc have also shown associations with nematode resistance in other breeds of sheep. Therefore, variation in...

Topics

Alleles
Animals
Base Sequence
Biological Evolution
DNA
Heterozygote
Homozygote
Host-Parasite Interactions
Major Histocompatibility Complex
Nematode Infections
Parasite Egg Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Sheep

Sheep Diseases

Source

Identifiers

PMID: 16099055
DOI: 10.1016/j.vetimm.2005.07.005

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