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Drosophila melanogaster Rac2 is necessary for a proper cellular immune response.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Aug 2005

Williams Michael J, Ando Istvan, Hultmark Dan

Abstract excerpt

It has been reported that during Drosophila embryonic development, and in cell culture, that the Rac GTPases are redundant. To better elucidate Rac function in Drosophila, we decided to study the role of Rac2 in larval cellular defense reactions against the parasitiod Leptopilina boulardi. Here we show a dramatic effect in the context of cellular immunity where, unlike embryonic development, Rac2 appears to have...

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Identifiers

PMID: 16098145
DOI: 10.1111/j.1365-2443.2005.00883.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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