Article
LRP 1 B functions as a receptor for Pseudomonas exotoxin.
Biochimica et biophysica acta - 25 Sept 2005
Pastrana Diana V, Hanson Alison J, Knisely Jane, Bu Guojun, Fitzgerald David J
Abstract excerpt
Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence factors, among them Pseudomonas Exotoxin A (PE). Previously, low-density lipoprotein receptor-related protein 1 (LRP 1) was shown to be the primary receptor for PE. In this report, we show that a close family member, LRP 1B, can also function as a receptor.
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