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Mouse Mammary Tumor Virus Infects Human Cells

1 Aug 2005

Abstract excerpt

Mouse mammary tumor virus (MMTV) has long been speculated to be involved in human breast cancer and more recently in human primary biliary cirrhosis. Despite complete proviral sequences markedly homologous to MMTV being identified in human breast cancer tissue, no convincing evidence has been presented to date that MMTV can infect human cells. Using both wild-type and a genetically marked virus (MMTV-EGFP), we...

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PMID: 16061645
DOI: 10.1158/0008-5472.can-04-2609

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