Article
Genetic factors in fetal growth restriction and miscarriage.
Seminars in thrombosis and hemostasis - 1 Jun 2005
Yamada Hideto, Sata Fumihiro, Saijo Yasuaki, Kishi Reiko, Minakami Hisanori
Abstract excerpt
Recently, several investigations concerning disadvantageous genetic factors in human reproduction have progressed. Inherited thrombophilia, such as factor V Leiden, prothrombin, and methylenetetrahydrofolate reductase mutations; gene polymorphisms of detoxification enzyme (CYP1A1); growth factors (insulin-like growth factor-I); and hormones such as angiotensinogen and CYP17 are involved in the pathogenesis of...
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