Article
Penetrance estimate of the fra(X) gene using Pointer versus direct estimate.
American journal of medical genetics - 1 Jan 2000
de Haan A F, Smits A P, Smeets D F, van Oost B A
Abstract excerpt
Direct estimate of the penetrance of the fra(X) gene was compared with the estimate using the Pointer computer program. Direct estimate gave overall penetrances of 85% for male and 64% for female carriers. The estimates calculated by the Pointer program were 82% for males and 38% for females. It...
Topics
- Female
- Fragile X Syndrome
- Gene Frequency
- Heterozygote
- Humans
- Intellectual Disability
- Intelligence
- Male
- Phenotype
- Software