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A unique case of der(11)t(11;22),-22 arising from 3:1 segregation of a maternal t(11;22) in a family with co-segregation of the translocation and breast cancer

1 Jan 2005

Abstract excerpt

OBJECTIVE: To report the first tertiary monosomy in a pregnancy loss to a female t(11;22) carrier. METHODS: The patient was a 34-year-old G10P1 female known to have a balanced translocation t(11;22)(q23;q11.2). She had one female livebirth (a translocation carrier) and eight miscarriages. Five female relatives known to be translocation carriers had a history of breast cancer, three of them premenopausally. The...

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PMID: 16049998
DOI: 10.1002/pd.1196

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A unique case of der(11)t(11;22),-22 arising from 3:1 segregation of a maternal t(11;22) in a family with co-segregation of the translocation and breast cancerPMID 16049998Read ↗

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