Association of chronic fatigue syndrome with human leucocyte antigen class II alleles.

doi:10.1136/jcp.2004.022681

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Article

Association of chronic fatigue syndrome with human leucocyte antigen class II alleles.

Journal of clinical pathology - 1 Aug 2005

Smith J, Fritz E L, Kerr J R, Cleare A J, Wessely S, Mattey D L

Abstract excerpt

BACKGROUND: A genetic component to the development of chronic fatigue syndrome (CFS) has been proposed, and a possible association between human leucocyte antigen (HLA) class II antigens and chronic fatigue immune dysfunction has been shown in some, but not all, studies. AIMS: To investigate the role of HLA class II antigens in CFS. METHODS: Forty nine patients with CFS were genotyped for the HLA-DRB1, HLA-DQA1,...

Topics

Adult
Alleles
Fatigue Syndrome, Chronic
Female
Gene Frequency
Genes, MHC Class II
Genetic Predisposition to Disease
Genotype
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Histocompatibility Testing

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Open in PubMed Open full text

Identifiers

PMID: 16049290
DOI: 10.1136/jcp.2004.022681
PMCID: PMC1770867

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