Article
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci.
Brain, behavior, and immunity - 1 Nov 2021
Hajdarevic Riad, Lande Asgeir, Rekeland Ingrid, Rydland Anne, Strand Elin B, Sosa Daisy D, Creary Lisa E, Mella Olav, Egeland Torstein, Saugstad Ola D, Fluge Øystein, Lie Benedicte A, Viken Marte K
Abstract excerpt
The etiology of myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is unknown, but involvement of the immune system is one of the proposed underlying mechanisms. Human leukocyte antigen (HLA) associations are hallmarks of immune-mediated and autoimmune diseases. We have previously performed high resolution HLA genotyping and detected associations between ME/CFS and certain HLA class I and class II...
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