Article
Phenotypic characterization of chondrosarcoma-derived cell lines.
Cancer letters - 26 Aug 2005
Schörle C M, Finger F, Zien A, Block J A, Gebhard P M, Aigner T
Abstract excerpt
Gene expression profiling of three chondrosarcoma derived cell lines (AD, SM, 105KC) showed an increased proliferative activity and a reduced expression of chondrocytic-typical matrix products compared to primary chondrocytes. The incapability to maintain an adequate matrix synthesis as well as a notable proliferative activity at the same time is comparable to neoplastic chondrosarcoma cells in vivo which cease...
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