Article
Selection of candidate genes in hypertension.
Methods in molecular medicine - 1 Jan 2005
Mein Charles A, Caulfield Mark J, Munroe Patricia B
Abstract excerpt
Essential hypertension is a common disease with multifactorial etiology affecting up to 10 million individuals in the United Kingdom alone. Current knowledge of the genetic contribution to this trait is restricted to a number of rare variants that produce hypertensive phenotypes in a Mendelian fashion and to genes highlighted by work on blood pressure regulation in rodent models. Recent advances in comparative...
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