Candidate Genes in the Pharmacogenomics of Antihypertensive Treatment - A Review and Future Aspects.

Abstract excerpt

Diversity in response to antihypertensive therapy is well-documented. Among many variables in the biological system, reasons include the genetic make-up of individuals. Although individual human genomes are 99.9% identical, the 0.1% difference predicts as many as three million polymorphisms. Some will affect protein expression or function, resulting in phenotypes affected for disease or with altered drug response....

Topics

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• Antihypertensive Agents
• Disease Models, Animal
• Genome-Wide Association Study
• Hormonal Regulation and Hypertension
• Hypertension
• Pharmacogenetics
• Pharmacogenetics and Drug Metabolism
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

4ee5354b-11e3-5b68-8d25-f57c4ea1cf32

DOI

10.2174/1570160043476123