Article
Transfection of chronic lymphocytic leukemic cells with myc and ras.
Leukemia - 1 Jan 1992
Zheng C Y, Skinnider L F, Xian J, Maksymiuk A
Abstract excerpt
Thirty samples of cells from twenty-one cases of chronic lymphocytic leukemia (CLL) were transfected with myc and/or ras. Transformation, as assessed by growth in liquid culture and change in morphology, occurred in only one case. Colony culture in semi-solid media, however, does not occur with t...
Topics
- Cell Transformation, Neoplastic
- Genes, myc
- Genes, ras
- Humans
- Karyotyping
- Leukemia, Lymphocytic, Chronic, B-Cell
- Phenotype
- Transfection
- Tumor Cells, Cultured