Article
Low renin-angiotensin system activity gene polymorphism and dysplasia associated with posterior urethral valves.
The Journal of urology - 1 Aug 2005
Peruzzi Licia, Lombardo Federica, Amore Alessandro, Merlini Emilio, Restagno Gabriella, Silvestro Leandra, Papalia Teresa, Coppo Rosanna
Abstract excerpt
PURPOSE: Obstructive uropathies, including posterior urethral valves (PUVs) and kidney hypodysplasia, are the most frequent cause of renal failure in children. The role of renin-angiotensin system genes in renal and urinary tract development has been observed in experimental models. The aim of this study was to investigate the distribution of angiotensin converting enzyme (ACE), angiotensinogen (AGT) and...
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