Article
Results of the DGTI workshop on the evaluation of the reactivity of monoclonal anti-D.
Infusionstherapie und Transfusionsmedizin - 1 Feb 1992
Sonneborn H H, Darda C, Ernst M, Flegel W A, Helmbold W, Kasulke D, Kühnl P, Mueller-Eckhardt C, Northoff H, Poschmann A
Abstract excerpt
All D+ samples were detected by all monoclonal antibodies without problems. Very few of the 3000 D- samples showed a +/- to ++ reaction with some of the IgG type mabs using the Coombs technique. It is still open whether these are specific reactions with weak positive samples, which were negative with polyclonal sera. IgM type mabs detected up to 100% of the Du samples dependent on the Rh-phenotype and the...
Topics
- Antibodies, Monoclonal
- Antibody Specificity
- Blood Grouping and Crossmatching
- Blood Transfusion
- Humans
- Isoantibodies
- Phenotype
